HLA-B73 Serotype B*7301 frequencies References Navigation menuHLA-BB*73016p21.31"Nomenclature for factors...
HLA-BB5B51B52B7B8B12B44B45B13B14B64B65B15B62B63B70B71B72B75B76B77B16B38B39B17B57B58B18B21B49B50B22B54B55B56B27B35B37B40B60B61B41B42B46B47B48B53B59B67B73B78B81B*82B*83
HLA-B alleles
HLABserotypeHLA-B22HLA-serotype tutorialB*18:06B*46:01B*55:03
major histocompatibility complex (human), class I, B73 | ||
| Alleles | B*7301 | |
Structure (See HLA-B) | ||
Symbol(s) | HLA-B | |
EBI-HLA | B*7301 | |
Locus | chr.6 6p21.31 | |
HLA-B73 (B73) is an HLA-B serotype. The serotype identifies the HLA-B*7301 gene product.[1] Part of B*7301 is similar to the HLA-B22 family, however part resembles the domains seen in other apes.[2] B73 is more common in Western Indian Ocean, Mediterranean and Africa. (For terminology help see: HLA-serotype tutorial)
Serotype
B*73:01 is one of the four B alleles that reacts with neither Bw4 nor Bw6. The others are B*18:06, B*46:01, and B*55:03.[3]
| B*73 | B73 | Other | Sample |
| allele | % | % | size (N) |
| 7301 | 22 | 69 | 106 |
B*7301 frequencies
| freq | ||
| ref. | Population | (%) |
| [5] | Parsi (Karachi, Pakistan) | 4.9 |
| [5] | United Arab Emirates | 2.0 |
| [5] | Italy | 2.0 |
| [5] | Seri (Sonora, Mexico) | 1.5 |
| [5] | Purépecha (Michoacán, Mexico) | 1.5 |
| [5] | Jews (Israel) (*2 studies) | 1.2 |
| [5] | Beti (Cameroon) | 1.1 |
| [5] | Casablanca (Morocco) | 0.9 |
| [5] | Tbilisi (Georgia) | 0.9 |
| [5] | Mossi (Burkina Faso) | 0.9 |
| [5] | Bulgaria | 0.9 |
| [5] | Sudanese | 0.8 |
| [5] | Tuva (Russia) (2) | 0.8 |
| [5] | Oman | 0.8 |
| [5] | Bamileke (Cameroon) | 0.6 |
| [5] | Pathan (Pakistan) | 0.5 |
| [5] | Khalkha (Mongolia) | 0.5 |
| [5] | Druse Arabs (Israel) | 0.5 |
| [5] | Baloch (Iran) | 0.5 |
| [5] | Manchester (England) | 0.5 |
| [5] | Algeria (1) | 0.5 |
| [5] | Turkey | 0.4 |
| [5] | Amman (Jordan) | 0.3 |
| [5] | Shona (Harare, Zimbabwe) | 0.2 |
| [5] | Republic of Macedonia | 0.2 |
| [5] | Nandi (Kenya) | 0.2 |
| [5] | Luo (Kenya) | 0.2 |
| [5] | Campania (Italy) | 0.2 |
| [5] | Greece | 0.2 |
References
^ Marsh SG, Albert ED, Bodmer WF, et al. (2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens. 65 (4): 301–69. doi:10.1111/j.1399-0039.2005.00379.x. PMC 2396006. PMID 15787720..mw-parser-output cite.citation{font-style:inherit}.mw-parser-output .citation q{quotes:"""""""'""'"}.mw-parser-output .citation .cs1-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png")no-repeat;background-position:right .1em center}.mw-parser-output .citation .cs1-lock-limited a,.mw-parser-output .citation .cs1-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Lock-gray-alt-2.svg/9px-Lock-gray-alt-2.svg.png")no-repeat;background-position:right .1em center}.mw-parser-output .citation .cs1-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Lock-red-alt-2.svg/9px-Lock-red-alt-2.svg.png")no-repeat;background-position:right .1em center}.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration{color:#555}.mw-parser-output .cs1-subscription span,.mw-parser-output .cs1-registration span{border-bottom:1px dotted;cursor:help}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/thumb/4/4c/Wikisource-logo.svg/12px-Wikisource-logo.svg.png")no-repeat;background-position:right .1em center}.mw-parser-output code.cs1-code{color:inherit;background:inherit;border:inherit;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;font-size:100%}.mw-parser-output .cs1-visible-error{font-size:100%}.mw-parser-output .cs1-maint{display:none;color:#33aa33;margin-left:0.3em}.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration,.mw-parser-output .cs1-format{font-size:95%}.mw-parser-output .cs1-kern-left,.mw-parser-output .cs1-kern-wl-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right,.mw-parser-output .cs1-kern-wl-right{padding-right:0.2em}
^ Hoffmann HJ, Kristensen TJ, Jensen TG, Graugaard B, Lamm LU (1995). "Antigenic characteristics and cDNA sequences of HLA-B73". Eur. J. Immunogenet. 22 (3): 231–40. doi:10.1111/j.1744-313X.1995.tb00237.x. PMID 8547229.
^ Voorter, CE; van der Vlies, S; Kik, M; van den Berg-Loonen, EM (October 2000). "Unexpected Bw4 and Bw6 reactivity patterns in new alleles". Tissue Antigens. 56 (4): 363–70. doi:10.1034/j.1399-0039.2000.560409.x. PMID 11098937.
^ derived from IMGT/HLA
^ abcdefghijklmnopqrstuvwxyzaaabac Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens. 61 (5): 403–7. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660. External link in|title=(help)
