Bamifylline See also References Navigation menu2016-63-9Interactive...

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Adenosine receptor antagonistsAlcoholsXanthinesRespiratory system drug stubsCardiovascular system drug stubs


drugxanthinechemical classselectiveadenosine A1 receptorantagonist
































































Bamifylline

Skeletal formula of bamifylline

Space-filling model of the bamifylline molecule
Names

IUPAC name
8-Benzyl-7-{2-[ethyl(2-hydroxyethyl)amino]ethyl}-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione

Identifiers

CAS Number



  • 2016-63-9 ☒N


3D model (JSmol)


  • Interactive image


ChEMBL


  • ChEMBL2110760 ☒N


ChemSpider


  • 15401 ☑Y


ECHA InfoCard

100.116.522


PubChem CID


  • 16229


UNII


  • ZTY15D026H ☑Y





Properties

Chemical formula

C20H27N5O3

Molar mass
385.46008
Pharmacology

ATC code


R03DA08 (WHO)

Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).


☒N verify (what is ☑Y☒N ?)

Infobox references



Bamifylline is a drug of the xanthine chemical class which acts as a selective adenosine A1 receptor antagonist.[1][2]



See also



  • Theophylline

  • Caffeine



References





  1. ^ Tomai, F; Crea, F; Gaspardone, A; Versaci, F; De Paulis, R; Polisca, P; Chiariello, L; Gioffrè, PA (June 1996). "Effects of A1 adenosine receptor blockade by bamiphylline on ischaemic preconditioning during coronary angioplasty" (PDF). European Heart Journal. 17 (6): 846–53. doi:10.1093/oxfordjournals.eurheartj.a014965. PMID 8781823..mw-parser-output cite.citation{font-style:inherit}.mw-parser-output .citation q{quotes:"""""""'""'"}.mw-parser-output .citation .cs1-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png")no-repeat;background-position:right .1em center}.mw-parser-output .citation .cs1-lock-limited a,.mw-parser-output .citation .cs1-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Lock-gray-alt-2.svg/9px-Lock-gray-alt-2.svg.png")no-repeat;background-position:right .1em center}.mw-parser-output .citation .cs1-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Lock-red-alt-2.svg/9px-Lock-red-alt-2.svg.png")no-repeat;background-position:right .1em center}.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration{color:#555}.mw-parser-output .cs1-subscription span,.mw-parser-output .cs1-registration span{border-bottom:1px dotted;cursor:help}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/thumb/4/4c/Wikisource-logo.svg/12px-Wikisource-logo.svg.png")no-repeat;background-position:right .1em center}.mw-parser-output code.cs1-code{color:inherit;background:inherit;border:inherit;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;font-size:100%}.mw-parser-output .cs1-visible-error{font-size:100%}.mw-parser-output .cs1-maint{display:none;color:#33aa33;margin-left:0.3em}.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration,.mw-parser-output .cs1-format{font-size:95%}.mw-parser-output .cs1-kern-left,.mw-parser-output .cs1-kern-wl-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right,.mw-parser-output .cs1-kern-wl-right{padding-right:0.2em}


  2. ^ Kofman, J; Grosclaude, M; Ouechni, MM; Perrin-Fayolle, M. "Comparative effects of bamifylline and theophylline on allergenic bronchospasm induced by the provocative inhalation test: double-blind cross-over study". Le Poumon et le Cœur (in French). 38 (3): 197–202. PMID 6752929.















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