Trans,polycis-polyprenyl diphosphate synthase ((2Z,6E)-farnesyl diphosphate specific) References External...
DimethylallyltranstransferaseThiaminase IMethionine adenosyltransferaseRiboflavin synthaseDihydropteroate synthaseSpermidine synthaseGlutathione S-transferaseFarnesyl-diphosphate farnesyltransferaseSpermine synthaseAlkylglycerone phosphate synthaseFarnesyltransferaseGeranylgeranyltransferase type 1Porphobilinogen deaminaseActive siteBinding siteCatalytic triadOxyanion holeEnzyme promiscuityCatalytically perfect enzymeCoenzymeCofactorEnzyme catalysisEC numberEnzyme superfamilyEnzyme familyList of enzymesOxidoreductaseslistTransferaseslistHydrolaseslistLyaseslistIsomeraseslistLigaseslist
EC 2.5.1
EC2.5.1.88enzymesystematic namecatalyseschemical reactionallylic
| Trans,polycis-polyprenyl diphosphate synthase ((2Z,6E)-farnesyl diphosphate specific) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.5.1.88 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Trans,polycis-polyprenyl diphosphate synthase ((2Z,6E)-farnesyl diphosphate specific) (EC 2.5.1.88) is an enzyme with systematic name (2Z,6E)-farnesyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 9--11 isopentenyl units).[1] This enzyme catalyses the following chemical reaction
- (2Z,6E)-farnesyl diphosphate + n isopentenyl diphosphate ⇌{displaystyle rightleftharpoons } n diphosphate + trans,polycis-polyprenyl diphosphate (n = 9 - 11)
This enzyme has the highest activity with (2Z,6E)-farnesyl diphosphate as allylic substrate.
References
^ Ambo, T.; Noike, M.; Kurokawa, H.; Koyama, T. (2009). "Cloning and functional analysis of cis-prenyltransferase from Thermobifida fusca". J. Biosci. Bioeng. 107 (6): 620–622. doi:10.1016/j.jbiosc.2009.02.006. PMID 19447338..mw-parser-output cite.citation{font-style:inherit}.mw-parser-output .citation q{quotes:"""""""'""'"}.mw-parser-output .citation .cs1-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png")no-repeat;background-position:right .1em center}.mw-parser-output .citation .cs1-lock-limited a,.mw-parser-output .citation .cs1-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Lock-gray-alt-2.svg/9px-Lock-gray-alt-2.svg.png")no-repeat;background-position:right .1em center}.mw-parser-output .citation .cs1-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Lock-red-alt-2.svg/9px-Lock-red-alt-2.svg.png")no-repeat;background-position:right .1em center}.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration{color:#555}.mw-parser-output .cs1-subscription span,.mw-parser-output .cs1-registration span{border-bottom:1px dotted;cursor:help}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/thumb/4/4c/Wikisource-logo.svg/12px-Wikisource-logo.svg.png")no-repeat;background-position:right .1em center}.mw-parser-output code.cs1-code{color:inherit;background:inherit;border:inherit;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;font-size:100%}.mw-parser-output .cs1-visible-error{font-size:100%}.mw-parser-output .cs1-maint{display:none;color:#33aa33;margin-left:0.3em}.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration,.mw-parser-output .cs1-format{font-size:95%}.mw-parser-output .cs1-kern-left,.mw-parser-output .cs1-kern-wl-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right,.mw-parser-output .cs1-kern-wl-right{padding-right:0.2em}
External links
Trans,polycis-polyprenyl+diphosphate+synthase+((2Z,6E)-farnesyl+diphosphate+specific) at the US National Library of Medicine Medical Subject Headings (MeSH)
